PRP + Hyaluronic Acid Injection: Heal & Protect Your Knee

PRP + Hyaluronic Acid Injection: Heal & Protect Your Knee

PRP + Hyaluronic Acid (HA) injection combines two powerful therapies in one treatment — your body’s own healing factors plus joint lubrication and cushioning.

It’s a non-surgical option for knee pain, osteoarthritis, and joint wear that addresses both repair and protection.

What is PRP?

PRP (Platelet-Rich Plasma) is made from your own blood. A small sample is drawn and spun in a centrifuge to concentrate the platelets — which contain:

• Growth factors — Stimulate tissue repair
• Healing proteins — Reduce inflammation and promote recovery
• Cytokines — Signal your body to regenerate

Because it’s from your own body, there’s virtually no risk of rejection or allergic reaction.

What is Hyaluronic Acid (HA)?

Hyaluronic acid is a natural substance found in your joint fluid. It acts as:

• Lubricant — Helps joints move smoothly
• Shock absorber — Cushions the joint during movement
• Protector — Coats cartilage to reduce friction and wear

In osteoarthritis, your natural HA decreases — leading to stiffness, pain, and grinding. HA injection restores what’s lost.

We use Monovisc — a high-quality, single-injection HA designed for long-lasting joint support.

Why Combine PRP + HA?

Each therapy works differently — together, they cover more ground:

PRP heals. HA protects. Together, they give your knee the best chance to recover and stay healthy.

How Does It Work?

1. Blood draw — Small sample taken from your arm
2. PRP preparation — Blood is spun to concentrate platelets (10–15 minutes)
3. Injection — PRP and HA are injected into the knee joint, often with ultrasound guidance
4. Recovery — Rest briefly, then resume light activities

The entire procedure takes about 30–45 minutes.

Who Can Benefit?

PRP + HA injection may help people with:

• Knee osteoarthritis (mild to moderate)
• Chronic knee pain and stiffness
• Cartilage wear and tear
• Sports injuries affecting the knee
• Joint grinding or clicking
• Those who want to delay or avoid knee replacement surgery

It’s not suitable for severe, bone-on-bone arthritis — but can provide significant relief for many patients.

What Does Research Say?

A 2020 study in The American Journal of Sports Medicine found that PRP + HA combination outperformed either treatment alone for knee osteoarthritis pain and function.

Research in Cartilage (2021) showed that the combination therapy provided longer-lasting relief — up to 12 months in many patients.

A 2019 meta-analysis in Journal of Orthopaedic Surgery and Research confirmed that PRP + HA significantly improved clinical outcomes compared to HA alone.

Sources:
Lana JF, et al. (2020). The American Journal of Sports Medicine.
Abate M, et al. (2021). Cartilage.
Chen Z, et al. (2019). Journal of Orthopaedic Surgery and Research.

What to Expect

1. Consultation — Assess your knee condition and medical history
2. Treatment day — Blood draw, PRP preparation, and injection (30–45 minutes total)
3. Recovery — Mild soreness for 1–2 days; avoid strenuous activity for 1 week
4. Results — Gradual improvement over 4–6 weeks; full benefits by 3 months
5. Follow-up — Monitor progress; repeat treatment if needed (typically every 6–12 months)

Most patients can walk out of the clinic and drive home the same day.

Is It Safe?

PRP + HA injection is minimally invasive with an excellent safety profile:

• PRP is from your own blood — no rejection risk
• HA is biocompatible and naturally found in your body
• No surgery, no general anesthesia
• Minimal downtime

Side effects are typically mild — temporary swelling, soreness, or bruising at the injection site.

Our Standards

At Reserve Daily, we use high-quality Monovisc HA and follow strict protocols for PRP preparation. Every treatment includes:

• Sterile, single-use PRP kits
• Medical-grade hyaluronic acid
• Doctor-led procedure with ultrasound guidance when needed

Learn more about our verification standards and how we work.

Explore our regenerative care treatments.

Disclaimer: This article is for educational purposes only. PRP and HA therapy results may vary. Consult a licensed healthcare professional before starting any treatment.